1.Ma Xinyu, Zhu Yuwei, Dong De, Chen Yan &Huang Zhiwei

Cryo-EM structures of two human B cell receptor isotypes

Science


2.Guo Minghui, Zhu Yuwei, Lin Zhiying, &Huang Zhiwei# 

Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT

Cell Research


3. Zheng Shanliang &Hu Ying# 

Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications

Trends in Cell Biology


4. Zhao Yanan &Yang Fan#    

A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1

Nature Communications


5. Zhu Xinyan &He Yuanzheng#

Structural basis of adhesion GPCR GPR110 activation by stalk peptide and G-proteins coupling

Nature Communications


6. Li Xinzhi, Ding Kaixin & Chen Zheng# 

Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis NASH

Nature Communications


7. Wang Na & He Yuanzheng#   

Structural basis of leukotriene B4 receptor 1 activation

Nature Communications


8. Chen Yan, Zhu Yuwei, Li Xiang, Gao Wenbo & Huang Zhiwei#  

Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility

Molecular Cell


9. Qian Yu & He Yuanzheng#           

Structural insights into adhesion GPCR ADGRL3 activation and GqGsGiG12 coupling

Molecular Cell


10.Xu Zhenmei, Tatsuya Ikuta & He Yuanzheng#      

Structural basis of sphingosine-1-phosphate receptor 1 activation and biased agonism

Nature Chemical Biology


11.Wang Xingwen, Zheng Shanliang & Hu Ying#      

LncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma

Molecular Therapy


12.Zheng Shanliang, Wang Xingwen & Hu Ying#      

iASPP suppression mediates terminal UPR and improves BRAF-inhibitor sensitivity of colon cancers

Cell Death and Differentiation


13.Setu M Vora & Shi Ming#

Targeting Stem-loop 1 of the SARS-CoV-2 5’UTR to suppress viral translation and Nsp1 evasion

Proceedings of the National Academy of Sciences of the United States of America


14.Zheng Shanliang & Hu Ying# 

iASPP suppresses Gp78-mediated TMCO1 degradation to maintain Ca2+ homeostasis and control tumor growth and drug resistance

Proceedings of the National Academy of Sciences of the United States of America


15.Wang Rui & Wei Lijun#  

An inulin-type fructan (AMP1-1) from Atractylodes macrocephala with anti-weightlessness bone loss activity

Carbohydrate Polymers


16.Zhao Kunming, Wang Xingwen, Zhao Dong& Hu Ying#     

lncRNA HITT Inhibits Lactate Production by Repressing PKM2 Oligomerization to Reduce Tumor Growth and Macrophage Polarization

Research


17.Zhang Boya & Gu Ning#

Malting barley carbon dots-mediated oxidative stress promotes insulin resistance in mice via NF-κB pathway and MAPK cascade

Journal of nanobiotechnology


18.Wei Xiangjuan & Gu Ning#

Di-(2-ethylhexyl) phthalate increases plasma glucose and induces lipid metabolic disorders via FoxO1 in adult mice

Science of the Total Environment


19.Li Xinzhi & Chen Zheng#      

Downregulation of the m6A reader protein YTHDC1 leads to islet β-cell failure and diabetes

Metabolism-clinical and experimental


20.Zhou Fengxia, Gan Rui, Zhang Fan & Huang Zhiwei# 

PHISDetector: A tool to detect diverse in silico phage-host interaction signals for virome studies

Genomics Proteomics Bioinformatics


21.Wang Ruiqi, Chen Boyang, Haiying Wei# & Tian Weiming#

Collecting and deactivating TGF-β1 hydrogel for anti‐scarring therapy in post-glaucoma filtration surgery

Materials Today Bio


22.Zhao Dong & Hu Ying#

iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation

Oncogene


23.Tian Hui & Tian Weiming#

Krüppel-like factor 7 deficiency causes autistic-like behavior in mice via regulating Clock gene

Cell & Bioscience


24.Zhao Qiong & Yang Qian#

Analysis of bacterial community functional diversity in late-stage shrimp (Litopenaeus vannamei) ponds using Biolog EcoPlates and PICRUSt2

Aquaculture