应我校生命科学与技术学院胡颖教授的邀请，美国泌尿生殖系统癌症研究中心的Anton Lennikov博士来我校进行学术交流，欢迎感兴趣的老师及同学参加！
报告题目：From ocularinflammation to cell death
时间：2015年11月17日（周二）下午3：30
地点：科学园2E栋405会议室
报告人简介：
Anton Lennikov博士，2013年于日本北海道大学获得博士学位，随后分别在日本札晃医科大学和美国泌尿生殖系统癌症研究中心进行博士后研究。不仅在Journal of leukocyte biology,Investigativeophthalmology & visual science,experimental eye research等国际著名杂志发表了多篇高水平研究论文，同时还是Histologyand Histopathology与MolecularVision两个杂志的专家评审人。
Research interest：
From control of ocularinflammation with naturally derived antioxidant compounds and syntheticsubstances such as NFkB inhibitors in animal models of ultraviolet inducedphotokeratitis and LPS induced uveitis that was my focus during my Ph.D., Imoved to work on changes in retina vascular tissue under metabolic changes oftype I diabetes as well as elucidating the role of lysosomal phospholipase A2in aqueous humor. Recently my work has shifted to cancer and normal cellbiology protein-protein interaction such as Complex I and II cell deathpathways and on non-canonical cell death pathways such as MLKL and severalother proteins.
代表性论文：
1. LennikovA, Hiraoka M, Abe A, Ohno S, Fujikawa T, Itai A, Ohguro H.IκBkinase-βinhibitor IMD-0354 beneficially suppresses retinal vascular permeability instreptozotocin-induced diabetic mice.2014 Sep 9;55(10):6365-73. doi: 10.1167/iovs.14-14671.
2. Dong Z, Iwata D, Kitaichi N, Takeuchi M,Sato M, Endo N, Iwabuchi K, Ando R, Fukuhara J, Kinoshita S, Lennikov A, Kitamura M, Mizuuchi K,Kanda A, Noda K, Namba K, Yamagishi S, Ohno S, Ishida S. Amelioration ofexperimental autoimmune uveoretinitis by inhibition of glyceraldehyde-derivedadvanced glycation end-product formation.J Leukoc Biol. 2014 Dec;96(6):1077-85. doi:10.1189/jlb.3A0513-288RRR. Epub 2014 Sep 8.
3. LennikovA, Kitaichi N, Noda K, Mizuuchi K, Ando R, Dong Z, Fukuhara J, Kinoshita S,Namba K, Ohno S, Ishida S. Amelioration of endotoxin-induced uveitis treatedwith the sea urchin pigment echinochrome in rats. Mol Vis. 2014 Feb 7;20:171-7.eCollection 2014.
4. LennikovA, Alekberova Z, Goloeva R, Kitaichi N, Denisov L, Namba K,Takeno M, Ishigatsubo Y, Mizuki N, Nasonov E, Ishida S, Ohno S. Single centerstudy on ethnic and clinical features of Behcet’s disease in Russia. ClinRheumatol. 2015 Feb;34(2):321-7.doi: 10.1007/s10067-013-2442-9. Epub 2013 Dec 10.
5. Hiraoka M, Abe A, LennikovA, Kitaichi N, Ishida S, Ohguro H. Increase of lysosomal phospholipase A2in aqueous humor by uveitis. Exp Eye Res. 2014 Jan;118:13-9. doi: 10.1016/j.exer.2013.09.018. Epub 2013 Oct 23.
6. FukuharaJ, Noda K, Murata M, Namba S, Kinoshita S, Dong Z, Ando R, Lennikov A, Kanda A, Ishida S. Tissue kallikrein attenuateschoroidal neovascularization via cleavage of vascular endothelial growthfactor. Invest Ophthalmol Vis Sci2013; 54(1):274-9.
7. Lennikov A, Kitaichi N, Kase S, Noda K, Horie Y, Nakai A, Ohno S, IshidaS. Induction of heat shock protein 70 ameliorates ultraviolet-inducedphotokeratitis in mice. Int J Mol Sci 2013; 14(1):2175-89.
8. Lennikov A, KitaichiN, Noda K, Ando R, Dong Z, Fukuhara J, Kinoshita S, Namba K, Mizutani M,Fujikawa T, Itai A, Ohno S, Ishida S. Amelioration of endotoxin-induced uveitistreated with an IkappaB kinase beta inhibitor in rats. Mol Vis 2012; 18:2586-97.
9. Lennikov A, KitaichiN, Fukase R, Murata M, Noda K, Ando R, Ohguchi T, Kawakita T, Ohno S, Ishida S.Amelioration of ultraviolet-induced photokeratitis in mice treated withastaxanthin eye drops. Mol Vis 2012; 18:455-64.
