隽立然

发布者:张宁发布时间:2021-08-20浏览次数:2637

联系方式    

邮箱:lrjuan@hit.edu.cn


个人简介

教育经历:

2003.9-2007.7   哈尔滨工业大学 计算机科学与技术专业 本科

2007.9-2009.7   哈尔滨工业大学 计算机科学与技术专业 硕士

2009.9-2015.3  哈尔滨工业大学 计算机科学与技术专业 博士


工作经历:

2015.5-2020.12   哈尔滨工业大学生命科学与技术学院  讲师

2020.12-至今   哈尔滨工业大学生命科学与技术学院  副教授

 

Personal Profile

EDUCATION:

B.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2003-2007

M.Eng.Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2007-2009  

Ph.D. Harbin Institute of Technology, Harbin, China, Computer Science and Technology, 2009-2015

 

ACADEMIC APPOINTMENTS:

Lecturer, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2015-2020

Associate Professor, Harbin Institute of Technology, Harbin, China, Biomedical Engineering, 2020-present

 

研究方向和领域

生物信息学

Bioinformatics

 

研究内容

主要研究方向为基因组大数据分析方法与软件,包括三方面内容:

1. 基因组学机器学习,研究机器学习算法在基因组学问题上的应用与改进;

2. 基因组注释与可视化,研究对容量庞大、格式多样、关系复杂的基因组大数据进行注释及可视化方法与软件;

3. 多组学数据分析,运用统计、计算方法,分析多组学数据、解决生物学问题。


Research Interests 

The major research area is methods and software of genome bigdata analysis, including 3 topics:

1. Machine learning in genomics: Improvement and application of machine learning algorithm for genomics.

2. Genome annotation and visualization: Annotation and visualization methods/software for genome bigdata with mass volume, various formats and complex relationship.

3. Multi-omics data analysis, Analyzing multi-omics data by computational and statistical methods, solving biological problem.

 

研究成果

代表性论文

1. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Wang, G., and Wang, Y.* (2020). Evaluating Individual Genome Similarity with a Topic Model. Bioinformatics.SCI检索)

2. Juan, L.*, Wang, Y., Jiang, J., Yang, Q.,Jiang, Q., and Wang, Y.* (2020). PGsim: A Comprehensive and Highly Customizable Personal Genome Simulator. Front Bioeng Biotechnol 8, 28.SCI检索)

3. Juan, L., Liu, Y., Wang, Y., Teng, M.,Zang, T., and Wang, Y. (2015). Family genome browser: visualizing genomes with pedigree information. Bioinformatics 31, 2262-2268. SCI检索)

4. Juan, L., Teng, M., Zang, T., Hao, Y.,Wang, Z., Yan, C., Liu, Y., Li, J., Zhang, T., and Wang, Y. (2014). The personal genome browser: visualizing functions of genetic variants. Nucleic Acids Res 42, W192-197. SCI检索)

5. Juan, L., Wang, G., Radovich, M.,Schneider, B.P., Clare, S.E., Wang, Y., and Liu, Y. (2013). Potential roles of microRNAs in regulating long intergenic noncoding RNAs. BMC Medical Genomics 6 Suppl 1,S7. SCI检索)

2019年度黑龙江省科学技术一等奖(排名4

 

开设的课程

生物信息学

Bioinformatics

生物数据库及软件应用基础

Foundation of Biological Database and Software

基因组信息学

Genome Informatics